ABSTRACT
Background: Head and neck cancers, primarily squamous cell carcinomas (HNSCC), represent a significant health burden, being localized predominantly on the mucosal surfaces of the head and neck region. Approximately 3% of all cancer cases reported worldwide are attributed to head and neck cancer. Aim: In this study, we aimed to characterize the demographics and histopathological features of patients with HNSCC. Material and methods: We reviewed histologically verified cases of HNSCC between 2010 and 2016 from the pathology archive of the County Emergency Hospital, Targu Mures. Data regarding the patients’ age, sex, tumor localization, histopathological type, and grade of differentiation were collected. Results: The majority of tumors were classic squamous cell carcinomas, with variants and mixed types also identified. The analysis revealed a predominance of male patients, along with a correlation between sex and tumor localization, and an association between age and specific tumor sites. Conclusions: Our findings underscore the importance of sex, age, and etiological factors in the development and management of HNSCC.