ABSTRACT
Introduction: Neurogenic heterotopic ossification (HO) is the abnormal formation of bone in non- skeletal tissues, typically near major joints, following traumatic or nontraumatic spinal cord or brain injuries. This condition significantly affects the patients’ quality of life, often leading to joint ankylosis and severe limitations of mobility. Case presentation: In June 2023, a 50-year-old construction worker fell from a height of 3 m and suffered multiple severe injuries, including an occipito-parietal cranium fracture with subsequent epidural and subarachnoid hematomas, a myelic fracture of the T11 and T12 vertebrae, traumatic anterolisthesis of the T11 vertebral body, and paraplegia. Following prehospital stabilization, he underwent lifesaving procedures, including a craniectomy for evacuation of the epidural hematoma and posterior stabilization of the thoracolumbar spine with decompressive laminectomy, at a trauma center in Budapest. By October 2023, rehabilitation efforts were hampered by extensive HO in the right hip, as confirmed by plain radiography. The patient was discharged in December 2023, with rehabilitation impossible due to the ankylosis of the right hip. At this advanced stage, surgical resection was identified as the only viable therapeutic option. Conclusion: Mature HO can only be effectively treated through surgical excision. Early diagnosis, prevention, and medical management of immature lesions are essential to avoid severe complications and preserve joint function.